I can't cite specifics but I've heard that, literally, smoking is hazardous to your health. It's not much different than tobacco smoke in that unhealthy residue in the smoke permeates the meat. From my own experience, the few times I've had smoked meat, I found that it didn't enhance the basic taste but did add another level of flavor at the edge which didn't really impress me. Is there more to it than that? Am I missing something?