After noting all the suggestions for restaurants in or near the Distillery District (thank you all - I hope you're not offended that I did not take any of your recommendations) we ended up at a small Italian place on Queen near River called Fusilli. I guess, in the end, I wanted something low key, unpretentious and simple. That, it is. There were 3 of us. We shared bruschetta (not bad, actually - even though I usually avoid it until tomatoes are local), escargots and mussels to start. The escargots were in a tomato garlic sauce and, well, I liked the sauce anyway. The mussels were outstanding. Fresh, plump and not overcooked in a tomato based sauce with hint of fennel. Really nice. Then we had 3 different pastas. My son had a sausage penne which he enjoyed (I forgot to taste it, so can't report); my husband had fusilli with salmon done in a white wine cream sauce - I thought the salmon was a bit overcooked and the sauce a little too thick, but he liked it; and I had their special which was green fettuccine with chicken and some other things - ok but not outstanding. Again, the chicken was a little overcooked and dry. With a bottle of serviceable Italian wine, it came to about $115 for all of us.
I'm not sure I'd make a point of going back there, but if I lived in the area or if I were going to an event at the Distillery area, I would consider it. A short walk or a 3 minute drive.