I just wanted to give some feedback, as I relied on some excellent advice from SF 'hounds when planning my itinerary.
Unfortunately, due to extended business and flight delays, my wife and I didn't get to try nearly as many places as we'd hoped. However, we had several excellent meals, including a dinner at Piperade (recommended by someone on this board) that truly was outstanding. The small plates were phenomenal, especially the foie gras with squid and the terrine. I had the seared tuna for a main course, which was very good. My SF friend (who dined with us that evening) had the rack of lamb, and afterward commented that it was the best meal that he'd had in SF (he has lived there for several years, but is a bachelor and doesn't frequently dine at high-end places). The atmosphere and service couldn't have been better, and I really was glad to have received this great recommendation.
Another great experience was at the Slanted Door. The food, service, and atmosphere were top notch. And the Ferry Building is awesome -- it really is a local treasure. My wife and I could have spent an entire day browsing there (and nearly did). We both agree that we definitely are in need of something similar here in Chicago.
On our last day, we enjoyed a great lunch at Scala's Bistro. I believe that this place has gotten mixed reviews. Maybe we're easy to please, but my wife and I both thought that the food and service were just great (and a great atmosphere -- the place was really hopping with a sophisticated mix of locals and tourists).
Finally, I just wanted to mention that, on our day trip to wine country, we had a great lunch at the girl and the fig. It really is a nice little spot, and I recommend it if you're in the area.
Thanks again to the SF 'hound who recommended Piperade, and I hope to get back to your fine city soon.