Here are joints that I've enjoyed in the past, but if anything new is on the scene please let me know:
Brigtsen's (beyond loved it for the roasted duck with tart dried cherry sauce and mashed potatoes, and the Ponchatoula strawberry shortcake, anything else great on the menu, what are your rec's here ?)
Kpaul's. (really liked it for his eponymous blackened fish as well as the coconut cake).
Brennan's (maybe it's no longer around, I haven't been in a while)
Dick and Jenny's.
Emeril's in the warehouse district.
August (which I didn't really like, go figure)
Fiorella's (I really liked the fried chicken here).
Acme Oyster House and Felix Oyster House (both were way way way overrated in my opinion).
Cafe du Monde, of course.
Crabby Jack's in Jefferson Parish (loved the drum fish in a hollandaise butter sauce and the shredded duck po boy and the barq's in the bottle, for some reason, i can't seem to get barq's in the bottle most anywhere).
Also is Rene Bistrot still around, or Stella or Stanley's, or Buster Holmes ???
One more thing is Mosca's worth the drive from NOLA and is it still good to go there if we will be having an all seafood/shellfish meal there ????