I know this must be a well worn path and subject. And I have been looking over previous posts...but my wife and I will be taking this route, driving we hope, and are looking for some interesting places to try out. We love to try new chefs who are just starting a new restaurant or something off the beaten path. We also like to try one high end place per city, something that is taking traditional and mixing it with something new, perhaps. Sounds like LA DEGUSTATION might be that place in Prague but any others would be helpful. Also if there are any recs for places that might be on route between any of the four cities mentioned that would be great. And if driving between these places is crazy for any reason feel free to bring that to our attention.
Thanks in advance for your help. Chowhounds has always directed us to great places we would never have found on our own.