Been in Rome for a few days, and went to our first recommended restaurant, 'Gusto 28 in Piazza Augusto Imperatore. It is a modern seafood and vegetarian restaurant, comparable in price and type of food to somewhere like Drago in Los Angeles.
We had the fried anchovies, the pacherri (kind of like a larger homemade rigatoni) with tomato and eggplant, the pacherri with artichoke hearts and mussels, the salt cod in a tomato broth, and the fried fish. All were excellent, and the first meal we've had here that we could not get in L.A. The pacherri and salt cod were particularly good. Although we did not have the whole branzino, it was prepared next to our table for two other parties, and it looked excellent (we woul probably order it if we went back)
One random note though. I had heard that portion sizes were smaller here in Europe, but I have not found it to be so. The size is consistent with what one would find at a similar restaurant in L.A (as opposed to someplace like Osteria Mozza, where the primi are very small). I have no idea how people manage to eat a primi and a secondi without getting huge.
Also, even with the euro (1.58 right now), the prices seem more or less in line with Los Angeles, a bit less than NY, and more than Chicago.