I made a brisket last night that requires cooking for 3-4 hours one day, removing from the oven and allowing it to cool, slicing and refrigerating overnight. Then...... you place it back in the oven for another 1 1/2 hours the next day before serving.
It came out of the oven at 11pm and I set it on a rack (wrapped in it's foil packet) to cool. Unfortunately, I went to bed and forgot to put it in the fridge until 6 am.It's now sliced and I am getting ready to cook it for the remainder.
I guess my question is regarding food safety. If any bacteria formed during the time it was not in the fridge, will cooking it at 375 kill whatever may have developed?