FIRST Time in Seattle

My wife and I are visiting Seattle for a four-day weekend in October. While I read the similar, recent post, what other advice would my fellow Chowhounds have for our visit?

We will definitely be trying Volterra (as per the other post), but would love further recommendations for:

-A good brewpub (or some pub serving NW beers);
-Lunch;
-Dinner---for an elegant "I love my wife" Saturday night;
-GREAT sushi and raw bar (area oysters)!

Lastly, I am not very familiar with the area (hence the trip), but what type of regional food should we NOT miss (i.e, trying steamed crabs when you are in my native Maryland)? For example, Geoduck clams?

Thank you in advance for helping me make this trip memorable!!! (If you need LA or Annapolis tips let me know).

David