O.K., here's the big one. Does anyone know for absolutely sure where the term, "muffaletta", came from? What does it mean in Italian? It is not in any of the many Italian dictionaries I've looked at and when I've been at the Central Grocery, I've never thought to ask. My guess is that is an Italian dialect term. There's an Italian word, "muffala", which is a mitt or something you stick your hands in to keep them warm in the winter. Could be that the sandwich is the same shape?