Originally from Connecticut and my pizza heaven, I now live in DC one of the most dismal pizza places on earth. With deference to the great Pepe's in New Haven, here are my two Hartford area recommendations:
Frankie's Pizza, South Road, Enfield Connecticut. (15 minutes north of Hartford. From I-91, exit King Street, head north on Route 5 for a few miles. There is an old, white, towering Congregational church at the corner of South. Head down South road a mile or two, and through two sets of lights; shopping center on left.
Frankie's has been around since the early 1960s if not before. Six of his previous restaurants were damaged in fires. The last restaurant of his to burn, Frankie's Firehouse, was surrounded by fire hydrants -- to no avail. His loyal local customers don't care about this history -- they just want Frankie's to quickly reopen. Frankie's sells his pizza at a fixed price; you order what you want on. His sizes are big. A small pizza, is a medium-sized pizza in any other restaurant. Cost: $10.60. (The last time I was there, Coor's light was $1 a glass during happy hour)
The best part of Frankie's pizza is the crust and the sauce. I love this pizza, it's simple, basic, not fancy -- but Frankie and sons have been making it for some 40 years now and they have it down right.
Other recommendation: Harry's Pizza, 1003 Farmington Ave., West Hartford. I know, I know, Luna's is great, so is First & Last, but Harry does a wonderful job. As good as the pizza is, Harry's salad is a must; their homemade dressing (if it isn't homemade correct me and then tell me where I can buy it ;-), is just incredible. Really. They should bottle it.