At someone's suggestion below (thanks for the suggestions too!), I'm re-posting with a little more specifics: I'm a Chicago-bound road tripper from Boston and I expect to be as far as the Albany-ish area at lunchtime.
I'm looking for something on the quick side, not too complicated, for a lunch break (Want to avoid the usual highway chain fare, of course). Any suggestions for sandwiches, cafes, and the like? I'm thinking Albany area (maybe not downtown though, I'm guessing that would add some time), but I can stop a bit before or a bit after for the right place.