25 of the World's Hottest Hot Sauces, Ranked

What do you get when you combine Carolina Reaper peppers, Trinidad Moruga Scorpion peppers and bhut jolokia ghost peppers with 9 million Scoville Plutonium Extract (concentrated capsaicin)? Well, for starters, you get an insanely spicy hot sauce. Mad Dog 357 celebrated their golden anniversary the spicy way — leaning into the signature burn that made them famous in the first place.